- Arylated γ-valerolactones (Agvls) moieties mainly used in agro-chemical and pharmaceutical industry
- 4-keto esters moieties act as a chemical intermediate for preparation of 1,4-dikotones
- 4,4-diaromatic substituted pentanoic acid and its esters have excellent scope in polymer industry
Various Agvls prepared from LA along with different aromatics such six membered (alkoxy/thio) and five membered (Thiophene and 2-methylthiophene) 4-keto ester (phenyl 4-oxopentanoate) prepared from LA with phenol 4,4-diaromatic substituted pentanoic acid and its esters prepared from LA and its esters with 2-methylthiophene
- Mild reaction conditions (85-150 °C)
- Reactions under open atmosphere
- Good conversion and yields
- Use of recyclable heterogeneous catalysts
- Use of excess aromatic in the reaction medium that acts as solvent and enhance the kinetics of the reaction with excellent selectivity that could be recycled
- Good chemo- and regio- selectivity for the preparation of Agvls.
- Good selectivity (>95%) for the preparation of 4,4-diaromatic substituted pentanoic acid along with total conversion of levulinic acid (LA)
- The prepared products of LA have structural accessibility to develop applications in the field of pharmaceuticals, agrochemicals and fuel industry.
- Agvls tested at 10 g scale and showed good conversion/selectivity
- 4,4-diaromatic substituted pentanoic acid (here aromatic 2-methylthiophene) is demonstrated at 25 g scale with 94% yield
4,4-diaromatic substituted pentanoic acid and its esters have excellent plasticizing ability and is potential alternative for commercially available DOP and BPA.
- The invention process is eco-friendly
- All the reactions conducted under neat conditions
- Excess used aromatics recycled/reused
Levulinic acid
Aromatic compounds
- Glass reactor with condensing assembly
- Distillation assembly (for separation of the products) or preparative flash chromatography
Tentative Price:
LA: ₹350/Kg; Aromatics: ₹100-500/Kg
Products: ₹1000-3000/Kg (depending on the usage/field)
Know-how for processes of arylated LA derivatives; Demonstration of the processes; Equipment necessary for pilot scale; License fee, royalty and other financial details are available on request.
